The additive role of dynamic contrast-enhanced and diffusion-weighted MR imaging in preoperative staging of breast cancer

Abstract Background In women with diagnosed breast cancer, accurate loco-regional staging and preoperative examination are of utmost importance for optimal patient management decisions. MRI may be warranted correct as recommended from international guidelines. DWI-MRI can combined CE-MRI to assess more functional data. So we aimed evaluate the performance qualitative in malignant lesions regards local extension disease axillary lymph node status, beyond standard assessment mammography ultrasound. This prospective study included 50 female patients pathologically proven (BIRADS VI) coming staging. Full-field digital (FFDM) ultrasound, CE-MRI, findings were compared all patients, evaluated independently. Results then correlated postoperative histopathology. Fifty enrolled this study; mean age population was 43.25 years. The divided into 2 groups: 37/50 (74%) underwent upfront surgery 13/50 (26%) received neoadjuvant therapy before surgery. All performed DCE breast. Among who surgery, DCE-MRI showed highest correlation pathology size overall sensitivity regarding multiplicity. Regarding therapy, found have concerning lesion multiplicity after completion chemotherapy cycles. Conclusion accurately map detect multifocality/multicentricity, thus tailor surgical options (either conservative or mastectomy). Qualitative DWI ultrasonography better evaluation nodal status.